Wednesday, June 26, 2013

Brain Cancer Hunger for Amino Acids Makes It More - BioSpace



6/25/2013 7:29:57 AM

Get the latest biotech news where you want it. Sign up for the free GenePool newsletter today!

An enzyme that facilitates the breakdown of specific amino acids makes brain cancers particularly aggressive. Scientists have discovered this in an attempt to find new targets for therapies against this dangerous disease. To fuel phases of fast and aggressive growth, tumors need higher-than-normal amounts of energy and the molecular building blocks needed to build new cellular components. Cancer cells therefore consume a lot of sugar (glucose A number of tumors are also able to catabolize the amino acid glutamine, an important building block of proteins. A key enzyme in amino acid decomposition is isocitrate dehydrogenase (IDH). Several years ago, scientists discovered mutations in the gene coding for IDH in numerous types of brain cancer. Very malignant brain tumors called primary glioblastomas carry an intact IDH gene, whereas those that grow more slowly usually have a defective form.

Hey, check out all the research scientist jobs. Post your resume today!



Source: http://www.biospace.com/news_story.aspx?StoryID=300966&full=1

braveheart roy orbison the third man 2012 nfl draft order mohamed sanu chris polk rueben randle

No comments:

Post a Comment

Note: Only a member of this blog may post a comment.